Despite federal moratorium, more Texas renters face eviction as state protection lapses
Juan Pablo Garnham, Texas Tribune
April 4, 2021
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Protesters place furniture and rally outside the Dallas office of Sen. John Cornyn, R-Texas, “to show him the reality of the eviction crisis” in this Sept. 1 file photo. Although the Center for Disease Control renewed its order halting evictions until the end of June, the Texas Supreme Court let state guidelines expire March 31. (Juan Figueroa/The Dallas Morning News/TNS)Juan Figueroa /Staff Photographer /TNS
Texans behind on their rent are at increasing risk of losing their homes despite a federal moratorium on evictions, according to housing attorneys, because a Texas Supreme Court order aimed at forestalling evictions has expired.
Targeting microRNAs makes cancer stem cells more susceptible to chemotherapies
Researchers in Italy have identified a pair of microRNA molecules that help maintain a population of cancerous stem cells that drive the growth of breast cancers and initiate tumor relapse after treatment. The study, which will be published April 2 in the
Journal of Cell Biology (
JCB), reveals that targeting these microRNAs makes cancer stem cells more susceptible to some chemotherapies and could potentially improve the prognosis of patients with aggressive forms of breast cancer.
Many tumors contain a small population of cancer stem cells that initiate tumor growth and give rise to the various cell types found in tumors. Moreover, because cancer stem cells are often resistant to radio- and chemotherapies, they can survive and promote tumor relapse and metastasis after initial rounds of treatment. In breast cancer, for example, tumors containing a relatively high number of cancer stem cells have a mu
Pesticide exposure during pregnancy might lead to the development of central nervous system tumors during childhood, according to a study involving researchers.
Combination of tumor cell vaccine and checkpoint therapy creates effective immune response
A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study for neuroblastoma and melanoma. The neuroblastoma model showed a 75% cure with long-term survival, researchers at Children s National Hospital found.
Myc is a family of regulator genes and proto-oncogenes that help manage cell growth and differentiation in the body. When Myc mutates to an oncogene, it can promote cancer cell growth. The Myc oncogenes are deregulated in 70% of all human cancers.
Treatment resistance in triple-negative breast cancers linked to softer tissue environment
Researchers at the University of California, San Francisco, have discovered that aggressive, triple-negative breast cancers (TNBCs) can evade treatment by reorganizing and softening the collagen matrix that surrounds the cancer cells. The study, which will be published April 2 in the
Journal of Experimental Medicine (
JEM), shows that the softer matrix activates a signaling pathway that promotes the cancer cells survival, and suggests that targeting this pathway could enhance the effectiveness of chemo- and radiotherapy in TNBC patients.
TNBC is an aggressive type of breast cancer with worse survival rates than other forms of the disease. Because TNBC cells lack the HER2 signaling receptor and the estrogen and progesterone hormone receptors, they cannot be eliminated by drugs that specifically target these proteins. Instead, TNBC patients are normally treated with a combination of surgery